Results 131 to 140 of about 40,520,256 (406)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

RISCOS OCUPACIONAIS E ALTERAÇÕES DE SAÚDE ENTRE TRABALHADORES DE ENFERMAGEM BRASILEIROS DE UNIDADES DEURGÊNCIA E EMERGÊNCIA

Ciencia y Enfermería
Objetivo: identificar os riscos ocupacionais existentes no ambiente de trabalho em Unidades Públicas de Urgência e Emergência e as alterações de saúde apresentadas pelos trabalhadores de enfermagem que ali atuam.
Rita de Cássia de Marchi Barcellos Dalri, Maria Lúcia do Carmo Cruz Robazzi, Luiz Almeida da Silva   +2 more
doaj   +1 more source

Results of Some Co-operative Work on Determination of Sulfur in Pyrites; Some Observations on Details of Manipulation, Sources of Error, and on Barium Sulfate as Precipitated under Different Conditions. [PDF]

, 1915
H. C. Moore
openalex   +1 more source

Building Performance and Work Motivation [PDF]

, 2018
Every company has a purpose,  the establishment of a company has a clear purpose. There are several things that suggest about the purpose of establishing a company. The company's first goal is to achieve maximum profit or profit as much as possible.
Hunein, H. (Hamida)
core  

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

What Correlative Laboratory Work is it Desirable to do? [PDF]

, 1921
M. M. McCool, G. W. Conrey, F. J. Alway
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

John McDonogh, His Life and Work.

, 1940
Mack Swearingen, William Talbott Childs
openalex   +2 more sources

Practice tests: do they work? Can they work better? [PDF]

, 2017
Within the diverse field of certification and licensure, millions of tests are administered each year by non-governmental bodies and state agencies. A perusal of relevant websites suggests that most of the major certification and licensure tests have ...
Karakolidis, Anastasios, O'Leary, Michael, Scully, Darina   +2 more
core  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source