Results 181 to 190 of about 3,416,683 (264)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Bidirectional relationship between burnout and perceived work ability: Evidence from a two-wave study among teachers. [PDF]

Appl Psychol Health Well Being
Hlado P, Lintner T, Juhaňák L, Harvankova K.   +3 more
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Work Ability in Young Adult Survivors (WAYS WF-10217): Documenting Labor Force Participation, Occupation, and Educational Attainment Following Cancer Treatment. [PDF]

J Adolesc Young Adult Oncol
Ingram KM, Tooze JA, Castellino SM, McLean KA, Salsman JM, Ghazal LV, Miller H, Wade JL, Behrens RJ, Sandberg JC, Strom C, Arcury TA, Lesser GJ, Danhauer SC.   +13 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Long-term work ability, cognitive impairments and work-related concerns among young adult cancer survivors: a comparative analysis with healthy controls (AYA-LE study). [PDF]

BMC Cancer
Brock H, Friedrich M, Geue K, Mehnert-Theuerkauf A, Richter D, Sender A, Leuteritz K.   +6 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Work Ability in the Digital Age: The Role of Work Engagement, Job Resources and Traditional and Emerging Job Demands Among Older White-Collar Workers. [PDF]

Behav Sci (Basel)
Di Tecco C, Marzocchi I, Russo S, Comotti A, Fattori A, Laurino M, Bufano P, Ciocan C, Ferrari L, Bonzini M.   +9 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Subjective and Objective Evaluation Of Physical Activity Level And Its Relationship With Work Ability Of Nurses In Different Hospital Departments. [PDF]

Med Lav
Rastimehr M, Mazloumi A, Kazemi Z, Chalak MH.   +3 more
europepmc   +1 more source