Results 231 to 240 of about 3,069,144 (284)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Hand Eczema and Self-Reported Work Ability in Middle-Aged Cohort: A Northern Finland Birth Cohort 1966 Study. [PDF]

Contact Dermatitis
Huuhtanen A, Huilaja L, Jokelainen J, Ala-Mursula L, Sinikumpu SP.   +4 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Return-to-Work among COVID-19 Survivors in the Philippines and the Role of Rehabilitation: A Mixed-method Design. [PDF]

Acta Med Philipp
Sy MP, Pineda RCS, Yao DPG, Togonon HD, Asaba E.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Discriminative Ability of the Charlson Comorbidity Index for Long-Term Mortality in a General Population: Nationwide, Population-Based Study of 10 Million Adults in Sweden. [PDF]

Clin Epidemiol
Westerberg M, Garmo H, Ludvigsson JF, Stattin P, Gedeborg R.   +4 more
europepmc   +1 more source

The current status and influencing factors of core competencies among China's internet-based "sharing nurses" based on social-ecological system theory: a multicenter cross-sectional study. [PDF]

Front Med (Lausanne)
Yudong W, Zhaowei X, Linlin J, Yishu Z, Jianghua W, Linlin Y, Chunling Y.   +6 more
europepmc   +1 more source

Rethinking emergency risk assessment: A single-center look at shock index and its variants in COVID-19. [PDF]

PLoS One
Belalcazar AT, Lasso VM, Álvarez Herazo JD, Clarete A, Figueroa-Paz R, Maya-Portillo D, Diez-Sepúlveda J.   +6 more
europepmc   +1 more source

The use of educational psychology-based STEAM education concept in the development of English curriculum resources. [PDF]

Sci Rep
Li Y.
europepmc   +1 more source