Results 61 to 70 of about 6,631,713 (291)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

PENGARUH KONSEP DIRI DAN KEDISIPLINAN TERHADAP KESIAPAN KERJA SISWA KELAS XI BIDANG KEAHLIAN ADMINISTRASI PERKANTORAN DI SMK HIDAYAH SEMARANG

open access: yesEconomic Education Analysis Journal, 2013
Tujuan penelitian ini adalah untuk mengetahui ada tidaknya pengaruh konsep diri dan kedisiplinan terhadap kesiapan kerja siswa baik secara parsial maupun simultan.
Iryandani Akhmad Sazali
doaj  

Professional self-concept of nurses: the influence of work stressors and related factors

open access: yesSichuan jingshen weisheng
BackgroundThe professional self-concept of nurses is a crucial indicator for their personal growth, development and career planning. Previous studies have shown that work stressors during the internship period may lead to a decrease in the level of ...
Chen Ji   +6 more
doaj   +1 more source

The deficit of decent work as a global problem of social and labor segment [PDF]

open access: yesInternational Economic Policy, 2016
The overview of the current trends in social and labor segment globally and in the Ukrainian economy is provided. The crises in functioning of the social and labor segment as the forms of expression of the deficit of decent work were isolated.
Anatoliy Kolot, Oksana Herasymenko
doaj  

A deficit of decent work as a current trend in the development of social and labor sphere in Ukraine [PDF]

open access: yesKnowledge & Performance Management, 2017
Sustainable development of the national economy is impossible without the creation of conditions for safe, high-quality, efficient work. The relevance of the study is explained by the need of methodological substantiation and development of theoretical ...
Anatoliy Kolot , Oksana Herasymenko
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Acerca de la evolución del concepto de actividad

open access: yesLaboreal, 2006
This article´s objective is to shed light on some elements of reflection about the current evolutions in the concept of activity, from an ergonomic perspective.
Pascal Béguin
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PENGARUH SUPERVISI KEPALA SEKOLAH DAN KONSEP DIRI TERHADAP DISIPLIN KERJA GURU PNS

open access: yesImprovement: Jurnal Ilmiah Untuk Peningkatan Mutu Manajemen Pendidikan, 2019
The objectives of this reseach are to study about the effects principal supervision and self-concept on work discipline of teachers of Civil Servants in State Junior High School of Cilacap Regency, Central Java.
Heni Rochimah   +2 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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