Psychosocial work factors and blood pressure among 63 800 employees from The Netherlands in the Lifelines Cohort Study. [PDF]
Faruque MO +7 more
europepmc +1 more source
Factors Influencing Social Mobility: Department for Work and Pensions Research Report 450 [PDF]
Bickerstaffe, T +4 more
core
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Exposure to Psychosocial Work Factors and Occupational Injury and Its Severity: Prospective Associations Among Employees in the French National Working Conditions Survey. [PDF]
Bertrais S, Niedhammer I.
europepmc +1 more source
Prospective associations between psychosocial work factors and self-reported health: study of effect modification by gender, age, and occupation using the national French working conditions survey data. [PDF]
Niedhammer I +2 more
europepmc +1 more source
Psychosocial work factors and sleep problems: findings from the French national SIP survey
É. Chazelle, J. Chastang, I. Niedhammer
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Working conditions of commercial drivers: a scoping review of psychosocial work factors, health outcomes, and interventions. [PDF]
Amoadu M, Sarfo JO, Ansah EW.
europepmc +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source

