Results 181 to 190 of about 27,156,344 (411)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Interplay of Adsorption Geometry and Work Function Evolution at the TCNE/Cu(111) Interface. [PDF]
J Phys Chem C Nanomater Interfaces, 2023 Niederreiter M +5 more
europepmc +1 more source
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
The welfare function of the South African government before and after apartheid
, 2000 Changing social-economic tendencies such as industrialisation and urbanisation, followed by poverty and a housing need, have since the turn of the century affected the social function of the South African govenunent.
De Necker, ICM, Ryke, EH, Van Eeden, ES
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The Help system and its Reflection Theory : A Sociological Observation of Social Work
, 2015 The relation between sociology and social work is analysed in this article as a relation between observer and object of observation. As a theoretical framework, we use Luhmannian systems theory, according to which modern society is characterised by ...
Schirmer, Werner, +1 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Prediction of the Effective Work Function of Aspirin and Paracetamol Crystals by Density Functional Theory-A First-Principles Study. [PDF]
Cryst Growth Des, 2023 Middleton JR +4 more
europepmc +1 more source
Effective functioning of a comprehensive system of cadastral work
, 2017 O. Stupen
openalex +2 more sources