Results 161 to 170 of about 16,416,515 (385)
Revista brasileira de enfermagem, 2007 This essay presents in a didactic way the constitution of work process in Nursing comprising: to manage, to assist, to research and to participate politically, presenting their elements and the interrelation among them, demonstrating that the work of Nursing is complex and multifaceted requiring a set of knowledge, skills and attitudes that are ...
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Investigation of perioperative work processes in provision of antibiotic prophylaxis: a prospective descriptive qualitative study across surgical specialties in Norway [PDF]
, 2019 Hilde Valen Wæhle +7 more
openalex +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
A Phase-space View of Cold-gas Properties of Virgo Cluster Galaxies: Multiple Quenching Processes at Work? [PDF]
, 2021 Kana Morokuma-Matsui +7 more
openalex +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
THE WORK PROCESS IN RADIOLOGICAL NURSING: INVISIBILITY OF IONIZING RADIATION
Texto & Contexto Enfermagem, 2015 Investigación cualitativa, descriptiva y exploratoria realizada con 20 profesionales de enfermería que actúan en los sectores de radiología general, centro quirúrgico, con el equipamiento de arco en “C” y el sector de hemodinamia de un hospital-escuela ...
Juliana Almeida Coelho de Melo +3 more
doaj
Crisis management in practice: a dynamic process intertwined with daily work performance [PDF]
, 2021 Olof Oscarsson
openalex +1 more source