Results 91 to 100 of about 23,609,372 (344)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Exploring Science : How science works

, 2009
Biblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 planta; 28014 Madrid; Tel.
Levesley, Mark, Johnson, Penny, Gray, Steve, Kearsey, Sue   +3 more
openaire   +1 more source

Women and Deliberative Water Management in Brazil [PDF]

, 2009
In this paper we consider some gender aspects of the evolution of water management in Brazil. In our work on women and water, we have been inspired by ecofeminist philosophy and the concept of 'feministThis research was supported by the Social Sciences ...
Moraes, A., Perkins, Patricia E. (Ellie)
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Pathways to support: a qualitative investigation of community health workers'role in coordinating disability services in India

Discover Social Science and Health
Aim To explore the roles and responsibilities of Accredited Social Health Activists (ASHAs) and Anganwadi Workers (AWWs) in providing support to people living with disability and their households.
Lorane Scaria, Rachel Blance-Palmer, Lynette Joubert, Saju Madavanakadu Devassy   +3 more
doaj   +1 more source

A Guide for Newcomers to Agent-Based Modeling in the Social Sciences [PDF]

This guide provides pointers to introductory readings, software, and other materials to help newcomers become acquainted with agent-based modeling in the social sciences.
Axelrod, Robert, Tesfatsion, Leigh
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Do occupational health and safety tools that utilize artificial intelligence have a measurable impact on worker injury or illness? Findings from a systematic review

Systematic Reviews
Background Artificial intelligence (AI) holds promise as a tool that can be used by practitioners in the field of occupational health and safety (OHS).
Arif Jetha, Hela Bakhtari, Emma Irvin, Aviroop Biswas, Maxwell J. Smith, Cameron Mustard, Victoria H. Arrandale, Jack T. Dennerlein, Peter M. Smith   +8 more
doaj   +1 more source

Strongly self-absorbing C*-dynamical systems, III [PDF]

, 2017
The work presented in this paper has benefited from a visit to the Department of Mathematics at the University of Kyoto in January 2016, and I would like to express my gratitude to Masaki Izumi for the hospitality and support.
Barlak, Blackadar, Brown, Dadarlat, Gardella, Gardella, Gábor Szabó, Izumi, Izumi, Izumi, Izumi, Izumi, Jones, Kirchberg, Matui, Matui, Matui, Matui, Ocneanu, Packer, Rørdam, Rørdam, Sato, Sato, Szabó, Szabó, Szabó, Tikuisis, Toms, Winter, Winter   +30 more
core   +3 more sources