Results 141 to 150 of about 8,881,373 (301)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
VIRGIL MADGEARU (1887-1940) FOUNDER OF THE ROMANIAN MANAGEMENT [PDF]
Characterized by eclectism and depth of scientific rigor, Professor Virgil Madgearu performed a remarkable activity in the economic sciences. Analyzing the efforts, the teaching and scientific work of the Romanian professor, his areas of expertise come ...
Gheorghe Gh. IONESCU, Mirela POPA
core
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Systematic Review on Social Support of Parent/Parents of Disabled Children
Journal of Rehabilitation, 2018 Objective Parents with a disabled child face many challenges, including the imbalance between work and leisure, limited social life and time limitations. Social support is a multidimensional index that shows the individual’s perception of being supported,
Fatemeh Gholami Jam +5 more
doaj
Arbor: Ciencia, Pensamiento y Cultura, 2008 This paper has the purpose of showing the identity between science and technology from within scientific language. The traditional philosophical argument in favour of this identity is briefly examined, through the work of Heidegger. Then, following Henri Atlan (“Ordres et Significations”, 1979. Le crystal et la fumée. Essai sur l’organisation du vivant.
openaire +1 more source
Stephen Hawking (1942-2018), Towards a Complete Understanding of the Universe
, 2018 Two of the major achievements of Stephen Hawking are described in elementary terms. They are his work on the beginning of the universe and his work on the end of black holes. These are perhaps the scientific achievements for which he is best known.
Hartle, James
core
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Health in Emergencies & Disasters Quarterly, 2017 Background: Experience of difficult incidents, besides its negative and adverse consequences, can have positive consequences and lead to the growth of people in several areas.
Mustafa Mardani +3 more
doaj