Results 71 to 80 of about 23,609,372 (344)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Francisco Salva's Electric Telegraph

, 2010
This article takes a look at the life and accomplishments of Francisco Salva of Spain, including his work with an electric telegraph system. The author states that information herein is based on the original report and some practical demonstrations that ...
Pérez Yuste, Antonio
core   +1 more source

The Future of Pharmaceutical Manufacturing Sciences

Journal of Pharmacy and Science, 2015
The entire pharmaceutical sector is in an urgent need of both innovative technological solutions and fundamental scientific work, enabling the production of highly engineered drug products. Commercial‐scale manufacturing of complex drug delivery systems (
J. Rantanen, J. Khinast
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Development of the QoLISSY 0–4 questionnaire: a health-related quality of life tool for young children with short stature

Journal of Patient-Reported Outcomes
Short stature in children aged 0–4 years presents unique physical, social, and emotional challenges that significantly impact health-related quality of life (HRQoL). The QoLISSY 0–4 questionnaire was developed as a Patient Reported Outcome measure (PROMS)
Adekunle Adedeji, Stefanie Witt, Julia Quitmann   +2 more
doaj   +1 more source

New directions for the treatment of adrenal insufficiency [PDF]

, 2015
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Allen, Allende, Badylak, Bancos, Berkes, Birke, Buaas, Chamoux, Chamoux, Clipsham, Cogger, Cox, Crawford, Drucker, Dubernard, El-Khairi, Else, Faulk, Fayard, Franksson, Freedman, Gallo-Payet, Gondo, Gondo, Grodstein, Guasti, Guasti, Hardy, Hardy, Hardy, Hardy, Hatano, Huang, Huang, Ibbertson, Jadhav, Kearns, Kim, King, Laufer, Ludwig, Luo, Mazilu, Parker, Sancho-Martinez, Schimmer, Schnabel, Sonoyama, Takahashi, Tanaka, Teebken, Thomas, Thomas, Thomas, Thomas, Thomas, Val, Val, Vierbuchen, Vouillarmet, Walczak, Walczak, Wei, Wilhelm, Wong, Yazawa, Yazawa, Yazawa, Yazawa, Zupekan   +69 more
core   +2 more sources

Coordinating Advanced Crowd Work: Extending Citizen Science

Hawaii International Conference on System Sciences, 2018
This paper presents a case study of an online citizen science project that attempted to involve volunteers in tasks with multiple dependencies including analyzing bulk data as well as interpreting data and writing a paper for publication. Tasks with more
Kevin Crowston, Erica Mitchell, Carsten S. Østerlund   +2 more
semanticscholar   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The intersection of intimate partner violence with sexual reproductive health in the Pacific: findings from a Kiribati population study

BMC Women's Health
Background Women who experience intimate partner violence (IPV) are likely to experience reduced sexual and reproductive health (SRH). This paper aims to describe the prevalence of IPV and family planning use, and explore how IPV intersects with SRH ...
Anneliese Spiteri-Staines, Luz Viviana Sastre Gomez, Jess Letch, Anna Bornemisza, Kristin Diemer   +4 more
doaj   +1 more source