Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Antecedents and consequences of work stress at PT Borneo Etam Samudera in Bontang
Jurnal Ekonomi dan BisnisThis research has two objectives. The first objective is to describe compensation and the physical work environment which are predictors of employee work stress.
Alfiana Damayanti +2 more
doaj +1 more source
, 1999 [Excerpt] “I’m stressed out.” The reality may be that the worker saying this is, in fact, experiencing an occupational illness. Many employees undergo stress as a normal part of their jobs, but some experience it more severely than others, to the point ...
Bureau of Labor Statistics
core +1 more source
Work Stress and Deviant Behaviour in Nursing Sector of Khyber Pakhtunkhwa, Pakistan [PDF]
, 2023 Zia ur Rehman +2 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
PENGARUH WORK LIFE BALANCE TERHADAP KEPUASAN KERJA DENGAN STRES KERJA SEBAGAI VARIABEL INTERVENING (Studi Pada PT. BPD Kalimantan Tengah Cabang Buntok) [PDF]
This research aims to determine how the work life balance, job satisfaction, and work Stress, the effect of the work life balance on job satisfaction, the effect of work life balance on work Stress, and the effect of work Stress on job satisfaction, and ...
Riyana, Nindi Dwi
core
WORK-RELATED STRESS, BURNOUT AND JOB SATISFACTION IN TURKISH MIDWIVES
, 2007 Selma Öncel, Zeynep Özer, Emine Efe
openalex +1 more source
The Mental Health and Well-being Benefits of Craft: a practice-based research project through the social probe of Lying flat as a response to work-related stress [PDF]
, 2023 Ziyan Wang
openalex +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Transitioning from recruit to officer: An investigation of how stress appraisal and coping influence work engagement [PDF]
, 2019 Susana Rodrigues +4 more
openalex +1 more source