Results 171 to 180 of about 513,054 (332)

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Cow-Related Injuries in Wisconsin During 2017-2023. [PDF]

Am J Ind Med
Modji KKS, McCoy K, Creswell PD, Collin MR, Tomasallo C, Bedno S.   +5 more
europepmc   +1 more source

Pregnancy and Emergency Department Utilization in North Carolina, 2016-2021: A Population-Based Surveillance Study. [PDF]

AJPM Focus, 2023
Nazzal EM, Waller AE, Meyer ML, Ising AI, Jones-Vessey K, Urrutia E, Urrutia RP.   +6 more
europepmc   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Proposed flowchart for the management of suspected work-related mental disorders: an experience report. [PDF]

Rev Bras Med Trab
Dias ACS, Gonçalves RE.
europepmc   +1 more source

Incorporation of privacy elements in space station design [PDF]

Privacy exists to the extent that individuals can control the degree of social contact that they have with one another. The opportunity to withdraw from other people serves a number of important psychological and social functions, and is in the interests
Caldwell, Barrett, Harrison, Albert A., Struthers, Nancy J.   +2 more
core   +1 more source

The implementation of workers’ health surveillance by occupational physicians

, 2023
Work can have a positive influence on health of workers, but can also negatively affect workers’ health, leading to impaired work functioning or sickness absence. Workers’ health surveillance (WHS) is a preventive strategy aimed at primary and secondary prevention of work-related health problems.
openaire   +3 more sources

Understanding and Overcoming Antibody‐Drug Conjugate Resistance: Biological Mechanisms and Emerging Analytical Frameworks in Breast Cancer

Advanced Science, EarlyView.
Antibody–drug conjugates (ADCs) transform breast cancer therapy, yet resistance limits their durability. Emerging evidence reveals that ADC failure is not solely tumor‐intrinsic but shaped by dynamic tumor–microenvironment interactions that alter drug delivery, processing, and response.
Minji Seo, Jangsoon Lee, Naoto T. Ueno
wiley   +1 more source

Influence of Sociodemographic Factors on Patient Completion of Patient-Reported Outcome Measures in Hand Surgery Patients. [PDF]

J Hand Surg Glob Online
Goodrich E, Smith T, Gudi M, Girma NM, Wilson C, Day CS.   +5 more
europepmc   +1 more source