Results 171 to 180 of about 1,314 (275)

Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine

open access: yesAdvanced Science, EarlyView.
This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng   +18 more
wiley   +1 more source

Pregnancy and Emergency Department Utilization in North Carolina, 2016-2021: A Population-Based Surveillance Study. [PDF]

open access: yesAJPM Focus, 2023
Nazzal EM   +6 more
europepmc   +1 more source

Morbidity and disability among workers 18 years and older in the services sector, 1997-2007 [PDF]

open access: yes
The National Institute for Occupational Safety and Health (NIOSH) is the Federal agency responsible for occupational safety and health research. In collaboration with its many partners, NIOSH is committed to the collection, analysis, dissemination, and ...

core  

RBM10 Deficiency Promotes Anti‐PD‐1 Resistance in LUAD via STING Alternative Splicing‐Driven CCL7 Signaling and Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
RBM10 deficiency promotes anti‐PD‐1 resistance in lung adenocarcinoma by altering STING alternative splicing, which enhances CCL7 secretion and CCR2‐dependent M2 macrophage polarization. A positive feedback loop via mitochondrial transfer sustains this immunosuppression.
Weitong Gao   +14 more
wiley   +1 more source

Morbidity and disability among workers 18 years and older in the agriculture, forestry, and fishing sector, 1997-2007 [PDF]

open access: yes
The National Institute for Occupational Safety and Health (NIOSH) is the Federal agency responsible for occupational safety and health research. In collaboration with its many partners, NIOSH is committed to the collection, analysis, dissemination, and ...

core  

MFPD: A Multiple Fungal Pathogen Detection Pipeline Across Diverse Habitats

open access: yesAdvanced Science, EarlyView.
The MFPD pipeline integrates a comprehensive ITS reference database of fungal pathogens, optimized parameters, and algorithms tailored for both full‐length and subregion sequences that balance accuracy and computational efficiency; it enables high‐throughput, species‐level identification from amplicon sequencing data, supporting large‐scale ...
Yi Shen   +13 more
wiley   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

open access: yesAdvanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li   +4 more
wiley   +1 more source

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