Results 61 to 70 of about 1,338 (232)

Family Health Strategy and Health Surveillance: knowledge of community and family physicians on Sanitary Surveillance, Environmental Health Surveillance and Surveillance of the Workers Health

, 2021
Introducción: La interacción entre los sectores del Sistema Único de Salud, en particular la Atención Primaria (AP) y la Vigilancia en Salud (VS), es fundamental para que las acciones que se enfocan en la integralidad sean operacionales en los servicios.
Ivancko, Giovanna Mendonça, Querino, Rosimár Alves, Silva, Gabrielly Cristiny Soares, Borges, Rafaela Defendi, Limongi, Jean Ezequiel   +4 more
openaire   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Challenges to the performance of health surveillance workers in health services

, 2022
Introduction: Health surveillance (Visa) is a primary function of the State for the protection of individual and collective health through risk control actions, current or potential, present in the production of goods and services, and is part of SUS (Brazilian Universal Health System).
Alves Costa, Ediná, Auxiliadora Magalhães Costa, Eliana, Karla Bomfm de Souza, Mariluce, Sodré Araújo, Patrícia, Santana Souza, Gisélia, Oyram Ramos Lima, Yara, Maria Santos da Paz, Bianca   +6 more
openaire   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Processo de vigilância em saúde do trabalhador

Cadernos de Saúde Pública
O presente texto insere-se na discussão da necessidade de aprofundamento das práticas de vigilância, muitas vezes, principalmente em países como o nosso, realizadas de forma empírica, carecendo de reflexão sobre suas bases técnicas e teóricas.
Jorge Mesquita Huet Machado
doaj  

Precarious employment and occupational injuries in the digital age ‒ where should we go from here?

Scandinavian Journal of Work, Environment & Health, 2018
There is growing demand for a clearer understanding of whether precarious work is a social determinant of health (1‒5) and whether non-standard workers with less job security are more vulnerable to adverse safety and health outcomes.
Helen Marucci-Wellman
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Health surveillance of workers

Thēmis, 2014
En nuestro ordenamiento jurídico, los derechos fundamentales a la vida y la salud delos trabajadores son dos bienes jurídicos importantes y no pueden ser desconocidos. Por ello, el Estado y los empleadores deben poner especial énfasis en la vigilancia de la salud yseguridad de los trabajadores para evitar que la relación laboral sea un obstáculo o una ...
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source