Results 101 to 110 of about 581,594 (305)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Enculturating a Protective Professional Community—Processes of Teacher Retention in a Swedish Hard-to-Staff School

Education Sciences
This study presented a positive deviant case: a Swedish hard-to-staff school which has had a low rate of teacher turnover over time. In line with the purpose of studying positive deviance in organisations, our exploratory inquiry was geared towards ...
Jeffrey Casely-Hayford, Per Lindqvist, Christina Björklund, Gunnar Bergström, Lydia Kwak   +4 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Employee workspace preferences in a mandated hybrid work policy: A discrete choice experiment

Scandinavian Journal of Work, Environment & Health
OBJECTIVE: Understanding employee workspace preferences is crucial for designing office work environments that meet their needs. This study investigated employee office design preferences within a mandated hybrid work model at a higher education ...
Emmanuel Aboagye, Willings Botha, Helena Ljungberg, Christina Danielsson, Irene Jensen   +4 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Safflower production under minimum and maximum soil preparation in Imperial Valley

California Agriculture, 1972
Yields of safflower (following cotton) produced under minimum tillage (at substantially reduced costs) remained as high as when the crop was produced under maximum tillage practices, according to the three-year study reported here.
G Worker, P Knowles
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Maximum vs. minimum tillage effects on barley and wheat in Imperial Valley

California Agriculture, 1974
THE OPTIMUM PLANTING time for wheat and barley in Imperial Valley is between December 15th and January 15th, which makes them excellent crops to follow cotton and late-plantings of grain sorghum.
G Worker, W Lehman
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

U.C. signal barley

California Agriculture, 1975
UC Signal barley, developed at the Imperial Valley Field Station, El Centro, within 40 miles of Mount Signal for which it was named, is well-adapted to the lower desert areas of California. In comparative tests over a 3- to 7-year period, it has shown an
G Worker, C Schaller
doaj