Results 61 to 70 of about 248,641 (304)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Business Ownership by Workers: Are Worker Cooperatives a Viable Option? [PDF]
One possible strategy for both succession and new business development is employee ownership. New business formation as an employee-owned firm or cooperative may have some advantages over formation as a sole proprietorship or partnership: pooling ...
Artz, Georgeanne M., Kim, Younjun
core
Political Economy : Variability and Consistency in the Development of Worker Owned Cooperatives [PDF]
, 2006 The relationship between worker cooperatives and their social and economic environment has sparked interest among the sociological community for the contradictions and harmony typical of these interactions. However, these studies do not examine how firm
Ramon, Cris
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Worker Self-Selection and the Profits from Cooperation [PDF]
We investigate a competitive labor market with team production. Workers differ in their motivation to exert team effort and types are private information.
Kosfeld, Michael, von Siemens, Ferdinand
core
Delaboring Republicanism [PDF]
, 2019 This article criticizes radical labor republicanism on republican grounds. I show that its demand for universal workplace democracy via workers’ cooperatives conflicts with republican freedom along three different dimensions: first, freedom to choose an ...
Taylor, Robert S.
core
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Assessment physical load of dockers in a worker cooperative
Revista Facultad Nacional de Salud Pública, 2011 Manual labourers are workers whose job consists of humping goods. Task commonly related to a varied level of mechanical stress due both to its mechanical stress demand and the workplace risk factors.
Hernán D. Zapata +2 more
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