Results 101 to 110 of about 48,032 (310)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

By Hook Or By Crook: From Pedicab Drivers to Company Owners through Start-Up Worker Co-Operatives

open access: yesPerformance, 2020
Disruption of information technology has threatened several jobsin the informal sector. As a result, the income gap between the rich and the poor can get wider.
Novita Puspasari, Yanuar E Restianto
doaj  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Los objetivos de una empresa gestionada por sus trabajadores : un análisis sobre el caso uruguayo [PDF]

open access: yes
The theoretical discussion concerning the comparison of employment and wage decisions between capitalist firms and worker cooperatives began with the seminal work of Ward (1958).
Andrés Dean, Gabriel Burdín
core  

Expanding Asset-Building: Opportunities Through Shared Ownership [PDF]

open access: yes, 2008
Based on a literature review and interviews, proposes expanding low-income working families' asset-building options beyond individual ownership to shared ownership such as cooperative housing.
Beadsie Woo, Heather McCulloch
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Differential Assessment of Wages for Members of Disabled People’s Artels During the New Economic Policy Period (Based on Materials from Astrakhan Province)

open access: yesВестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения
Introduction. In the article the differential assessment of the dynamics of the average earnings of the members of the disabled people’s artels of the Astrakhan province in 1923–1928 is carried out. Methods and materials.
Ekaterina Popova
doaj   +1 more source

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Limb girdle muscular dystrophy type R9 (LGMDR9) results from biallelic variants in FKRP. There is limited data to predict loss of ambulation (LOA) among those with LGMDR9. Methods Participants in an ongoing dystroglycanopathy natural history study (NCT00313677) with FKRP variants who had achieved ambulation and were more than 3 ...
Chandra L. Miller   +6 more
wiley   +1 more source

A comparison of the efficiency of producers under collective and individual modes of organisation [PDF]

open access: yes
This paper compares collective and individuals production systems' technical and allocative efficiency. The producers being studied belong to Honduran agrarian reform cooperatives engaging in colective and/or individual maize production.
Michael Martin, Timothy G. Taylor
core  

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