Results 61 to 70 of about 48,032 (310)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Efficiency in employee-owned enterprises: An econometric case study of Mondragon [PDF]

open access: yes, 2011
We provide the first econometric study of efficiency for a member of the Mondragon group of worker cooperatives. Eroski is a retail distribution chain and, most unusually, there are two distinct types of hypermarkets: (i) cooperatives with significant ...
Arando, Saioa   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

LA TRIBUTACIÓN DE LAS EMPRESAS DE PARTICIPACIÓN DE LOS TRABAJADORES (COOPERATIVAS DE TRABAJO Y SOCIEDADES LABORALES): APUNTES PARA UNA REFORMA / TAX TREATMENT OF WORKER’S OWNED ENTERPRISES (WORKER COOPERATIVES AND WORKER SOCIETIES): NOTES FOR A REFORM. [PDF]

open access: yesRevista de Estudios Cooperativos, 2010
Las empresas de participación de los trabajadores (cooperativas de trabajo asociado y sociedades laborales) cumplen objetivos económicos y sociales valorados por la Constitución española y por el Derecho comunitario que justificarían un tratamiento ...
Pilar ALGUACIL MARÍ
doaj  

Labour Managed Firms in Spain [PDF]

open access: yes
There are at least two types of companies: conventional capitalist companies or Profit Maximizing Firms (PMFs) and, on the other hand, companies managed by their workforce or Labour-Managed Firms (LMFs).
Alfonso Carlos Morales Gutiérrez   +2 more
core  

Cities Building Community Wealth [PDF]

open access: yes, 2015
As cities struggle with rising inequality, widespread economic hardship, and racial disparities, something surprising and hopeful is also stirring.
Majorie Kelly   +2 more
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Des entrepreneurs qui ont « le cœur à la bonne place » : enquête sociologique sur les pratiques d’intérêt général parmi les entrepreneurs en coopératives de travail au Québec

open access: yesRevue Interventions Économiques
Building on cases in the province of Quebec, Canada, this article illustrates the analytical contributions of a qualitative sociology of knowledge approach to the study of "general interest" practices among entrepreneurs in worker cooperatives.
Louis Rivet-Préfontaine
doaj   +1 more source

Home-care interventions: which participation? Social workers and parents discuss about an ongoing action-research

open access: yesEncyclopaideia, 2017
Home-care interventions are carried out for a fixed amount of weekly hours by the home-care worker within the family, in the perspective of giving support to the parents and contributing to the care plan.
Andrea Petrella, Sara Serbati
doaj   +1 more source

Business Ownership by Workers: Are Worker Cooperatives a Viable Option? [PDF]

open access: yes
One possible strategy for both succession and new business development is employee ownership. New business formation as an employee-owned firm or cooperative may have some advantages over formation as a sole proprietorship or partnership: pooling ...
Artz, Georgeanne M., Kim, Younjun
core  

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