Results 111 to 120 of about 1,284,641 (318)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Characterizing Informatics Roles and Needs of Public Health Workers

, 2015
Brian E. Dixon, Timothy D. McFarlane, Shandy Dearth, Shaun J. Grannis, P. Joseph Gibson   +4 more
openalex   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Relationship and predictive value of controlling nutritional status score and serum vitamin level with coronary heart disease in young and middle-aged adults

BMC Nutrition
Objective To investigate the relationship between CONUT score and serum vitamin (25-OHD, folic acid, vitamin B12) levels and CHD in young and middle-aged adults, and to analyze the value of CONUT score combined with serum vitamin (25-OHD, folic acid ...
Jie Deng, Xiaoming Liu, Haining Liu, Wei Lu   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Worker Voice - workers' newspaper

, 2003
Este artigo pretende reconstruir os artigos publicados no jornal comunista "A Voz Operária", que regista o fim da Federação dos Trabalhadores do Rio Grande do Sul (FORGS).
openaire   +1 more source

Essential Workers [PDF]

Family Medicine, 2020
openaire   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Efficacy of an online cognitive behavioral therapy program developed for healthcare workers during the COVID-19 pandemic: the REduction of STress (REST) study protocol for a randomized controlled trial [PDF]

, 2020
Luisa Weiner, Fabrice Berna, Nathalie Nourry, François Séverac, Pierre Vidailhet, Amaury C. Mengin   +5 more
openalex   +1 more source

The unwritten rules and HIV: a qualitative study of informal institutions and HIV vulnerability among workers at social venues in Uganda [PDF]

, 2023
Susan Babirye, Kristien Michielsen, Freddie Ssengooba   +2 more
openalex   +1 more source