Results 141 to 150 of about 4,630,847 (264)

Justice (Vol. 1, Iss, 6) [PDF]

, 1919
International Ladies Garment Workers Union (ILGWU)
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Differences in cardiorespiratory fitness, physical activity, and pulmonary function across occupational groups and educational levels: a cross-sectional study. [PDF]

Ann Med
Chróścielewska N, Chomiuk T, Laprus-Abramska K, Pałasz D, Mamcarz A, Śliż D.   +5 more
europepmc   +1 more source

Justice (Vol. 5, Iss. 22) [PDF]

, 1923
International Ladies Garment Workers Union (ILGWU)
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Justice (Vol. 3, Iss. 20) [PDF]

, 1921
International Ladies Garment Workers Union (ILGWU)
core   +11 more sources

The Critical Role of Race-Conscious Framework in Advancing Mental Health Workforce Diversity: A Case Study. [PDF]

Race Soc Probl
Kyere E, Asad Z, Fukui S.
europepmc   +1 more source

Justice (Vol. 6, Iss. 31) [PDF]

, 1924
International Ladies Garment Workers Union (ILGWU)
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Lived Experiences of Deathcare Workers in Managing Infectious Dead Bodies. [PDF]

Public Health Chall
Botha NN, Segbedzi CE, Dumahasi VK, Kodom RV, Ogum MA, Maneen S, Tsedze IS, Akoto LA, Ansah EW.   +8 more
europepmc   +1 more source