Results 181 to 190 of about 1,284,641 (318)

Combining professionalization and personalization in English long-term care: analyzing stakeholder views through a workforce lens. [PDF]

Front Sociol
Kispeter E, Hussein S.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Does your job really matter? Job-specific cancer incidence among a cohort coal mine workers in Queensland, Australia. [PDF]

Int Arch Occup Environ Health
Glass DC, Gwini SM, Del Monaco A, Fritschi L, Abramson MJ, Sim MR, Walker-Bone K.   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Workplace stress, support and stress management strategies for healthier lifestyles among healthcare workers in Ethiopia. [PDF]

PLoS One
Birhanu Z, Mekonen H, Kavishe RA, Lien L, Andersen LS, Mushi DL, Dræbel TA, Tucho GT.   +7 more
europepmc   +1 more source

외국인력 및 이민 유입의 경제적 영향 (Economic Effects of Foreign Workers and Immigrants in Korea)

, 2012
Kyungsoo Choi
openalex   +1 more source

The Effect of Gender Role Attitudes on Multidimensional Leadership Orientations Among Pre-hospital Emergency Medical Services Worker

Kadir Okan Bağış, Süreyya Gümüşsoy, Gülbin Gökçay, Teslime Cakaloglu, Hande Kekreli Goyloson, Mahmut Gümüş, Ertugrul Erik   +6 more
openalex   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Evaluation of the HIV Case-Based Surveillance System in Dire Dawa City Administration, Ethiopia. A Descriptive Cross-Sectional Study. [PDF]

AIDS Res Treat
Hagos F, Kassahun A, Sisay A.
europepmc   +1 more source

Psychological Contract and Workers Commitment in Oil Companies in Nigeria

, 2019
Ukpong Uwem Johnson, Ossai Ignatius, Simon Hart Emmanuel, Ossia Ethelbert Nduka   +3 more
openalex   +1 more source