This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Prevalence of hypertension and associated factors among sanitation workers: a community based cross-sectional survey in five urban regions of Nepal. [PDF]
Khatri S +7 more
europepmc +1 more source
Justice (Vol. 2, Iss. 25) [PDF]
International Ladies Garment Workers Union (ILGWU)
core +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Effect of containment strategies for respiratory diseases on infections imported via international travel to the USA: a modelling study. [PDF]
Koiso S +7 more
europepmc +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Experienced teammates increase productivity in remote work: Evidence from a full remote work company in Japan. [PDF]
Ishikura H.
europepmc +1 more source
Justice (Vol. 6, Iss. 32) [PDF]
International Ladies Garment Workers Union (ILGWU)
core +2 more sources
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Inadequacy of interventions to eliminate or reduce violence against healthcare professionals by patients and/or their relatives. [PDF]
Yöyen E, Barış TG.
europepmc +1 more source

