Results 61 to 70 of about 4,630,847 (264)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

Diagnostic value of plasma-derived exosomal miR-223 for epithelial ovarian cancer

BMC Women's Health
Objectives To evaluate the diagnostic value of plasma exosomal miR-223 and its combination with CA125 for the diagnosis of early-stage epithelial ovarian cancer (EOC).
Li Yang, Zhihong Yang, Zhihui Liu, Na Qi, Lili Tao   +4 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Some outcomes and a hypothetical mechanism of combined lead and benzo(a)pyrene intoxication, and its alleviation with a complex of bioprotectors

Toxicology Reports, 2020
Rats were exposed 3 times a week during 6 weeks to repeated intraperitoneal injections of lead acetate solution in water (Pb) and/or benzo(а)pyrene solution in petrolatum oil (B(а)P) in various dose ratios.
Ilzira A. Minigalieva, Tatiana N. Shtin, Oleg H. Makeyev, Vladimir G. Panov, Larisa I. Privalova, Vladimir B. Gurvic, Marina P. Sutunkova, Tatiana V. Bushueva, Renata R. Sakhautdinova, Svetlana V. Klinova, Svetlana N. Solovyeva, Ivan N. Chernyshov, Eugene A. Shuman, Artem A. Korotkov, Boris A. Katsnelson   +14 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Graves' Disease-Associated Acute Necrotizing Ulcerative Gingivitis A Case Report

International Dental Journal
Introduction: Acute necrotizing ulcerative gingivitis (ANUG) is predominantly observed in immunocompromised individuals, with antithyroid drug-induced cases being exceptionally rare.
Hongxia Wei, Xiaodan Qin
doaj   +1 more source

A Case Report of Lung Cancer in a Horse Trainer Caused by Exposure to Respirable Crystalline Silica: An Exposure Assessment

Safety and Health at Work, 2013
Here, we present a case of lung cancer in a 48-year-old male horse trainer. To the best of our knowledge, this is the first such case report to include an exposure assessment of respirable crystalline silica (RCS) as a quartz.
Jin-Ha Yoon, Boowook Kim, Byung-Soon Choi, So Young Park, Hyun-Suk Kwag, In-Ah Kim, Ji Yeon Jeong   +6 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Gender differences in occupational exposure to carcinogens among Italian workers

BMC Public Health, 2018
Background Many carcinogenic chemicals are still used or produced in several economic sectors. The aim of this study is to investigate differences in occupational exposure patterns to carcinogens by gender in Italy.
Alberto Scarselli, Marisa Corfiati, Davide Di Marzio, Alessandro Marinaccio, Sergio Iavicoli   +4 more
doaj   +1 more source