Advanced Functional Materials, EarlyView.PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source
An autonomous agentic workflow for clinical detection of cognitive concerns using large language models. [PDF]
NPJ Digit MedTian J +12 more
europepmc +1 more source
Scalable Thermal Engineering via Femtosecond Laser‐Direct‐Written Phononic Nanostructures
Advanced Functional Materials, EarlyView.This study demonstrates that femtosecond laser‐induced periodic surface structures (fs‐LIPSS) can function as phononic metasurfaces, reducing thermal conductivity below the plain thin‐film limit. Phonon Monte Carlo analysis reveals that the periodic structures restrict phonon mean free paths.
Hiroki Hamma +4 more
wiley +1 more source
How threshold customisation affects the performance of a multiclass X-ray AI model for primary care triage: a retrospective study. [PDF]
BMJ OpenSim JZT +8 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.Permanent magnets derive their extraordinary strength from deep, universal electronic‐structure principles that control magnetization, anisotropy, and intrinsic performance. This work uncovers those governing rules, examines modern modeling and AI‐driven discovery methods, identifies critical bottlenecks, and reveals electronic fingerprints shared ...
Prashant Singh
wiley +1 more source
Lessons learned from implementing FAIRification workflows in diabetes research in Germany. [PDF]
PLOS Digit HealthInau ET +10 more
europepmc +1 more source
Advanced Functional Materials, EarlyView.This study introduces VIVID (Vesicle In Vivo Identification using DNA), a qPCR‐based platform that tracks PCR‐amplifiable DNA tags loaded in the EVs for accurate and quantifiable EV biodistribution in vivo. ABSTRACT Extracellular vesicles (EVs) represent promising carriers for nucleic acid therapeutics, offering advantages over synthetic nanoparticles ...
Oscar Boyadjian +5 more
wiley +1 more source
Impact of a dedicated consult shift on reducing time to resolution of diagnostic disagreements: A quality improvement initiative. [PDF]
World J Clin CasesVirarkar M +8 more
europepmc +1 more source
Unveiling Multidimensional Physicochemical Design Principles for Tissue Processing Hydrogels
Advanced Functional Materials, EarlyView.This study establishes a materials‐based design framework for polymer hydrogels in tissue clearing, linking physicochemical properties to performance in tissue processing, labeling, and imaging. By analyzing rheology, swelling, porosity, antibody diffusion, mechanical performance, and thermochemical stability across platforms, this work provides a ...
Sangjae Kim +8 more
wiley +1 more source
Comparative evaluation of two MALDI-TOF MS systems for microbial identification: accuracy and workflow efficiency in a clinical microbiology laboratory. [PDF]
Microbiol SpectrKöffer J +8 more
europepmc +1 more source