Results 31 to 40 of about 686,759 (258)

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

Methods for Proteogenomics Data Analysis, Challenges, and Scalability Bottlenecks: A Survey

IEEE Access, 2021
Big Data Proteogenomics lies at the intersection of high-throughput Mass Spectrometry (MS) based proteomics and Next Generation Sequencing based genomics.
Muhammad Usman Tariq, Muhammad Haseeb, Mohammed Aledhari, Rehma Razzak, Reza M. Parizi, Fahad Saeed   +5 more
doaj   +1 more source

common-workflow-language/cwltool: 3.1.20211103193132

, 2021
What's Changed Bump eWaterCycle/setup-singularity from 6 to 7 by @dependabot in https://github.com/common-workflow-language/cwltool/pull/1554 skip pyparsing 3.x to fix pydot; rdflib's sparql parsing by @mr-c in https://github.com/common-workflow ...
Thomas Hickman, Kapil kumar, Brad Chapman, Miguel Boland, Farah Zaib Khan, Tomoya Tanjo, Denis Yuen, Rupert Nash, Andrey Kartashov, Gijs Molenaar, Manvendra Singh, Guillermo Carrasco, Alejandro Barrera, bogdang989, Michael Kotliar, Dan Leehr, Stian Soiland-Reyes, Hervé Ménager, John Chilton, Michael R. Crusoe, boysha, ash, Peter Amstutz, Nebojsa Tijanic, Joshua C. Randall, Pau Ruiz Safont, Giacomo Tagliabue, Chuck McCallum, James J Porter   +28 more
core   +1 more source

“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.
Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith   +8 more
wiley   +1 more source

A Review on Task Scheduling Techniques in Cloud and Fog Computing: Taxonomy, Tools, Open Issues, Challenges, and Future Directions

IEEE Access, 2023
Efficient task scheduling on the cloud is critical for optimal utilization of resources in data centers. It became even more challenging with the emergence of 5G and IoT applications that generate massive number of tasks with stringent latency ...
Zulfiqar Ali Khan, Izzatdin Abdul Aziz, Nurul Aida Bt Osman, Israr Ullah   +3 more
doaj   +1 more source

common-workflow-language/cwltool: 3.1.20230127121939

, 2023
What's Changed Keep track of which files have already been parsed by @tetron in https://github.com/common-workflow-language/cwltool/pull/1786 Move sys.exit by @jfennick in https://github.com/common-workflow-language/cwltool/pull/1772 --write-summary to ...
Thomas Hickman, Kapil kumar, Brad Chapman, Miguel Boland, Farah Zaib Khan, Tomoya Tanjo, Denis Yuen, Rupert Nash, Bruno P. Kinoshita, Andrey Kartashov, Gijs Molenaar, Manvendra Singh, Guillermo Carrasco, bogdang989, Michael Kotliar, Dan Leehr, Stian Soiland-Reyes, Hervé Ménager, John Chilton, Michael R. Crusoe, boysha, Kevin Hannon, ash, Peter Amstutz, Nebojsa Tijanic, Joshua C. Randall, Pau Ruiz Safont, Chuck McCallum, Tijanic, Nebojsa, Chilton, John, Safont, Pau Ruiz, Spotify, kumar, Kapil, Kotliar, Michael, Boland, Miguel, Carrasco, Guillermo, Yuen, Denis, McCallum, Chuck, University of Manchester, Kartashov, Andrey, Khan, Farah Zaib, Nash, Rupert; id_orcid, Edinburgh Parallel Computing Centre, Singh, Manvendra, Randall, Joshua C., Ménager, Hervé, Crusoe, Michael R., Kinoshita, Bruno P., Hannon, Kevin, Molenaar, Gijs, College of Science and Engineering, Amstutz, Peter, Soiland-Reyes, Stian, Barcelona Supercomputing Center, Chapman, Brad, Tanjo, Tomoya, Leehr, Dan, Cincinnati Children's Hospital Medical Center, Hickman, Thomas   +58 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Healthcare resource utilization analysis in newly diagnosed mantle cell lymphoma: resource alleviation with adoption of the TRIANGLE ibrutinib regimen without autologous stem cell transplantation

Annals of Hematology
For younger, fit patients with mantle cell lymphoma (MCL), first-line therapy includes high-dose chemotherapy (HDCT) and autologous stem cell transplantation (ASCT).
Jonas Wißkirchen, Nora S. Rogmann, Michael Greiling, Frederic Ries, Anke Ohler, Georg Hess, Julia Osygus   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Effects of the Interactions Between LPS and BIM on Workflow in Two Building Design Projects [PDF]

, 2014
Variability in design workflow causes delays and undermines the performance of building projects. As lean processes, the Last Planner System (LPS) and Building Information Modeling (BIM) can improve workflow in building projects through features that ...
Khan, Sheriz, Tzortzopoulos, Patricia
core   +5 more sources