Results 111 to 120 of about 7,297,432 (370)
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Age‐Related Changes in Myeloid Cells and Their Impact on Subcutaneous Melanoma Growth in Mice
Aging and Cancer, EarlyView.Our findings reveal that age‐related changes in subcutaneous melanoma growth and immunotherapy response are context‐dependent. In models where tumor growth and treatment resistance increase with age, this effect is partly driven by enhanced immunosuppression from myeloperoxidase‐active Gr‐1⁺ myeloid cells.
Kaitlyn M. Landreth +7 more
wiley +1 more source
Practice Recommendations for Genetic Testing of Ataxias
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan +7 more
wiley +1 more source
DIGITALIZATION IN THE CONSTRUCTION INDUSTRY
Вестник Северо-Кавказского федерального университета, 2022 Construction is an industry that includes a huge number of stages in the life cycle of a project, and if you apply appropriate technologies based on numbers on each of them, you can optimize each of them by applying an information technology model, whose
I. Kravchenko
doaj
CaGrid Workflow Toolkit: A taverna based workflow tool for cancer grid
BMC Bioinformatics, 2010 Background In biological and medical domain, the use of web services made the data and computation functionality accessible in a unified manner, which helped automate the data pipeline that was previously performed manually. Workflow technology is widely
Sulakhe Dinanath +6 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Paroxysmal kinesigenic dyskinesia (PKD) is the most common hereditary paroxysmal movement disorder. The PRRT2 gene is the first identified causative gene and accounts for the majority of PKD. In this study, we investigated the pathogenicity of PRRT2 variants in the splice regions. Methods Patients with clinically suspected PKD and no
Jiao‐Jiao Xu +5 more
wiley +1 more source
Semi-supervised spatio-temporal CNN for recognition of surgical workflow
EURASIP Journal on Image and Video Processing, 2018 Robust and automated surgical workflow detection in real time is a core component of the future intelligent operating room. Based on this technology, it can help medical staff to automate and intelligently complete many routine activities during surgery.
Yuwen Chen, Qi Long Sun, Kunhua Zhong
doaj +1 more source
Mapping Light Communication SLA-Based Workflows onto Grid Resources with Parallel Processing Technology [PDF]
, 2008 Dang Minh Quan +2 more
openalex +1 more source
Towards an Intelligent Workflow Designer based on the Reuse of Workflow Patterns [PDF]
, 2007 In order to perform process-aware information systems we need sophisticated methods and concepts for designing and modeling processes. Recently, research on workflow patterns has emerged in order to increase the reuse of recurring workflow structures ...
Chiao, C. +5 more
core +4 more sources