Results 81 to 90 of about 7,297,432 (370)

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Surgical instrument counting: Current practice and staff perspectives on technological support

Human Factors in Healthcare
Background: Surgical instrument counting is a manual, attention-intensive task of the operating room (OR) nurse. Many labour-saving technologies have been proposed, but implementation remains challenging.
A.M. Kooijmans, L. de Rouw, M. van der Elst, J.J. van den Dobbelsteen   +3 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Mining Event Logs to Support Workflow Resource Allocation

, 2012
Workflow technology is widely used to facilitate the business process in enterprise information systems (EIS), and it has the potential to reduce design time, enhance product quality and decrease product cost. However, significant limitations still exist:
Brin, Chaudhuri, Chung, Cook, Geng, Gray, Greco, Han, Huang, Jiawei, Lee, Liu, Liu, Omiecinski, Russell, Stadtler, Thompson, Tingyu Liu, van der Aalst, van der Aalst, van der Aalst, van der Aalst, van der Aalst, van der Aalst, van der Aalst, van der Aalst, Van Nieuwenhuyse, Vandaele, Wang, Witten, Wu, Yalong Cheng, Yang, Zhonghua Ni   +33 more
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Using workflow technology to manage flexible e-learning services [PDF]

, 2002
Workflow technology provides a suitable platform to define and manage the coordination of business process activities. We introduce a flexible e-learning environment – called Flex-eL – that has been built upon workflow technology.
Ho, C., Lin, J., Orlowska, M. E., Sadiq, W.   +3 more
core  

Toward a first-principles integrated simulation of tokamak edge plasmas [PDF]

, 2008
Performance of the ITER is anticipated to be highly sensitive to the edge plasma condition. The edge pedestal in ITER needs to be predicted from an integrated simulation of the necessary first-principles, multi-scale physics codes.
A Khan, A Kritz, A Pankin, A Shoshani, A Sim, Aymar R, C Docan, C Jin, C Reinhold, C S Chang, Chang C S, D Keyes, D Schultz, D Silver, D Stotler, D Zorin, E D' Azevedo, E Feibush, E Yoon, F Hinton, G Bateman, G Park, Greenwald M, H Abbasi, H Strauss, H Weitzner, J Cummings, J Lofstead, K Bennett, K Schwan, Klasky S, L Greengard, L Sugiyama, Leonard A W, Lofstead J, M Adams, M Nagappan, M Parashar, M Pindzola, M Vouk, M Wolf, N Podhorszki, P Krsti, P Mouallem, P Worley, Park G Y, R Barreto, R Samtaney, S Ethier, S Klasky, S Ku, S Parker, Shoshani A, T Hahm, T Lao, W Lee, Y Chen, Y Xiao, Z Lin   +58 more
core   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Benefits of connecting rfid and lean principles in health care [PDF]

, 2005
The performance management process in health care is far behind compared to the manufacturing and service industries. Although nowadays the health care organizations are able to deal with a greater rank diseases, their cost, quality and delivery has ...
Aguado Correa, Francisco, Barcos, Lucía, Álvarez Gil, María Joséfa   +2 more
core   +1 more source