Results 91 to 100 of about 2,257,354 (296)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Experimental Study on Vibration Characteristic of Gearbox of High-speed Train Under Different Working Condition

Jixie chuandong, 2019
The vibration characteristic of gearbox of high-speed train under different working conditions is studied. With a gearbox of a certain type of high-speed train as the object, the main influence factors of vibration are studied by the method of combining ...
Lin Xinhai Zhao Yongqiang Ma Yuqiang Dong Ting
doaj  

Galaxy Mass, Metallicity, Radius and Star Formation Rates

, 2012
Working with 108,786 Sloan Digital Sky Survey low redshift galaxies we have examined the relation between galaxy mass, metallicity, radius, and star formation rates primarily in the central portions of galaxies.
Aihara, Allen, Blitz, Bolatto, Bouché, Brooks, Cowie, Dalcanton, Drew Brisbin, Ellison, Genel, Juvela, Kennicutt, Kewley, Klypin, Krumholz, Krumholz, Leier, Leitner, Leroy, Madore, Martin Harwit, Parravano, Peng, Peng, Robertson, Savaglio, Shi, Tremonti, Wong, Yates   +30 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Algebraic quantum permutation groups

, 2007
We discuss some algebraic aspects of quantum permutation groups, working over arbitrary fields. If $K$ is any characteristic zero field, we show that there exists a universal cosemisimple Hopf algebra coacting on the diagonal algebra $K^n$: this is a ...
Bichon, Julien
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Characteristics of Traffic Flows at Kuda Mati non-traffic light Intersection in Workhour and Holidays

E3S Web of Conferences, 2018
Characteristics of traffic flow needs to be revealed to describe the traffic flow that occurred at the research location. One of the patterns of traffic flow movement of Merauke Regency that is important enough to be observed is the movement pattern that
Herbin F. Betaubun
doaj   +1 more source

Menstrual characteristics and night work among nurses

INDUSTRIAL HEALTH, 2015
Night work has been associated with adverse effects in terms of reproductive health. Specifically, menstruation has been suggested to be negatively impacted by night work, which again may influence fertility. This study investigated whether working nights is related to menstrual characteristics and if there is a relationship between shift work disorder
MOEN, Bente E., BASTE, Valborg, MORKEN, Tone, ALSAKER, Kjersti, PALLESEN, Ståle, BJORVATN, Bjørn   +5 more
openaire   +3 more sources