Results 151 to 160 of about 2,260,402 (296)

FEATURE EXTRACTION AND ESTABLISHMENT BASED ON PUMPING UNIT WORKING CONDITIONS AND GLOBAL FAULT IDENTIFICATION

Jixie qiangdu
In response to the challenging task of fault feature classification in the current working conditions of pumping units，which results in poor adaptability and low recognition rate of the established diagnosis model.
REN Taizhu, FAN Jun, JIANG Xiaxin
doaj  

Low-pressure plasma cleaning of organic contamination from chemically coated surfaces: a study combining experimental and molecular dynamics studies. [PDF]

RSC Adv
Wang Z, Li Y, Zhang P, Wang F, Sun L, Bai Q, Zhu M, Wang B.   +7 more
europepmc   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Enhanced Microwave Commutation Quality Factor of Tunable Capacitors Based on SrTiO₃ Thin Films. [PDF]

Molecules
Tumarkin A, Bogdan A, Sapego E, Korepanov O, Karamov A.   +4 more
europepmc   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Two-Dimensional Metastable-Phase Nickel Hexagonal Nanosheets for Highly-Performance Electrochemical Acetone Hydrogenation. [PDF]

Nat Commun
Chen L, Zhang Z, Li P, Luo H, Li C, Pan S, Huang WH, Pao CW, Yang H, Hu Z, Shao Q.   +10 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Endoscopic laser lithotripsy for an impacted pancreatic duct stone using a novel ultra-slim cholangiopancreatoscope via the minor papilla. [PDF]

Endoscopy
Ogura T, Nakamura J, Kanadani T, Bessho K, Nishikawa H.   +4 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The disaster law and control measures of high-stress tunnels in fault areas: a case study. [PDF]

Sci Rep
Li W, Yao M, Liao Z, Wu J, Ma N, Su J, Mei C, Wang W.   +7 more
europepmc   +1 more source