Results 221 to 230 of about 2,257,354 (296)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

High-Sensitivity Air-Coupled Ultrasonic Transducer Design Based on PMN-PT Bending Vibration Modes. [PDF]

Sensors (Basel)
Deng J, Chen X, Zhu Y, Wang X, Han T, Luo C.   +5 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Risk Factors for Nonunion Following Lateral Locked Plating of Distal Femoral Fractures: A Bayesian Analysis of 560 Patients. [PDF]

J Bone Joint Surg Am
Wagner RK, Janssen SJ, Cote M, Borgida JS, Tung WS, Kloen P, Weaver MJ, Harris MB, Aneja A, Ly TV, Distal Femur Research Group.   +10 more
europepmc   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Partial Oxidation-Engineered Dendritic α-Fe₂O₃@Fe Photoanode: Enhanced Photoelectrochemical Water-Splitting Performance and Pt-Modified Stability. [PDF]

Nanomaterials (Basel)
Yang Y, Zheng Y, Zhao M, Yu X, Li S, Zheng J.   +5 more
europepmc   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Psychometric Evaluation of the Patient-Experienced Continuity of Care Questionnaire (PECQ) Using Rasch Model. [PDF]

Health Expect
Ljungholm L, Ekstedt M, Fagerström C, Djukanovic I, Årestedt K.   +4 more
europepmc   +1 more source