Results 231 to 240 of about 2,257,354 (296)

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Changed Serum Levels of Sirtuin1 and Sirtuin3 and Their Correlations with Sleep Quality and Cognitive Function in Patients with Chronic Insomnia Disorder. [PDF]

Nat Sci Sleep
Liu GX, Zhang Y, Song Y, Yang S, Su AX, Feng YZ, Zhou YS, Ma ZJ, Xia L, Chen GH.   +9 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Eye-Tracking-Based Cognitive Assessment Predicts the Risk of Memory Decline: A Community-Based Cohort Study. [PDF]

Geriatr Gerontol Int
Katsuhisa M, Teshirogi S, Yamamoto S, Oyama A, Ito Y, Ikegawa Y, Okawara M, Nakajima T, Nakatani Y, Bando H, Tanaka S, Hashimoto M, Iwata K, Takeda S.   +13 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

Overemployment and underemployment of part-time pharmacists: Prevalence and connection to work-life characteristics. [PDF]

Explor Res Clin Soc Pharm
Mott DA, Doucette WR, Alhersh E, Arya V, Bakken BK, Gaither C, Kreling DH, Schommer JC, Witry M.   +8 more
europepmc   +1 more source

Influence of Thermal Inertia on Dynamic Characteristics of Gas Turbine Impeller Components. [PDF]

Entropy (Basel)
Liu Y, Jia Y, Liu Y.
europepmc   +1 more source

Favorable changes in health- and work-related factors and subsequent work ability in midlife and older social and health care employees. [PDF]

Int Arch Occup Environ Health
Poutanen J, Härmä M, Lallukka T, Joensuu M, Haukka E, Koskinen A, Ervasti J, Shiri R.   +7 more
europepmc   +1 more source

Gel-immersion-assisted laser ablation of a self-expandable metal stent using a novel 3-o'clock-channel cholangioscope. [PDF]

Endoscopy
Ogura T, Bessho K, Nakamura J, Nguyen Trong N, Nishikawa H.   +4 more
europepmc   +1 more source

Neural Network-Enabled Process Flowsheet for Industrial Shot Peening. [PDF]

Materials (Basel)
Feltner L, Mort P.
europepmc   +1 more source