Results 61 to 70 of about 7,008,070 (297)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Defining Working-Class Literature(s): A Comparative Approach Between U.S. Working-Class Studies and Swedish Literary History

open access: yesNew Proposals, 2016
The aim of this article is to contribute to the theoretical understanding of the phenomenon of working-class literature through a comparison of how it has developed in two countries—Sweden and the United States—and, more importantly, how it has been ...
Magnus Nilsson, John Lennon
doaj  

The evolution of the mood of the Izhevsk-Votkinsk workers in October 1917–December 1918 [PDF]

open access: yesОмский научный вестник: Серия "Общество. История. Современность"
The article examines the problem of determining the views of Izhevsk-Votkinsk workers in 1917–1918, which led them to participate in the anti-Soviet uprising of 1918.
N. A. Zayats
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

What does it mean to be working class? Exploring the definition of a social class identity through the eyes of working-class professional services and administrative staff in Russell Group universities

open access: yes, 2023
What it means to have a working-class identity in the UK today is constantly under tension and debate. From socio-economic proxies used by large organisations as determinants of disadvantage to POLAR data, self identification and other metrics, academic ...
Pilgrim-Brown, Jess
core   +1 more source

Education for Mobilization: The Effects of Knowledge about Labor History on Union Support

open access: yesBritish Journal of Political Science
The US working class is less organized along class lines than in other advanced democracies. We propose a new explanation: the absence of education on historical class struggle and labor organizing weakens support for the contemporary labor movement.
Roxanne Rahnama, Jonne Kamphorst
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

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