Results 201 to 210 of about 205,992 (252)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Justification trajectories for pension inequality in Chile (2016-2023): the role of social class and beliefs in meritocracy. [PDF]

Front Sociol
Castillo JC, Canales-Sellés R, Laffert A, Urzúa T.   +3 more
europepmc   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Measuring and understanding labor exploitation on a sample of workers in the Costa Rican fishing industry. [PDF]

PLoS One
Abeyta S, Moton LN, Dank M.
europepmc   +1 more source

Association between socioeconomic status and cardiovascular disease by sex: Mediating roles of psychological and behavioral factors. [PDF]

PLoS One
Choi J, Cho SI.
europepmc   +1 more source

A novel generative oversampling for software defect prediction. [PDF]

Sci Rep
Goyal SR.
europepmc   +1 more source

The ARGO dataset: Annotated and delineated intracardiac electrograms of post-ischemic ventricular tachycardia. [PDF]

PLoS One
Orrù M, Baldazzi G, Zirolia D, Bertagnolli L, Viola G, Solinas MG, Pani D.   +6 more
europepmc   +1 more source

Patient Preferences for Treatment in Relapsed/Refractory Acute Leukemia: A Multinational Discrete Choice Experiment. [PDF]

Patient Prefer Adherence
Nier S, Hussain H, Hussain H, Hitch J, Chowdhury S, Skedgel C, Mott DJ.   +6 more
europepmc   +1 more source

Who is worthy of protection? Revisiting a theoretical model on the social origins of health inequities during the COVID-19 pandemic. [PDF]

Scand J Public Health
Gauffin K.
europepmc   +1 more source