Results 81 to 90 of about 205,992 (252)

The Philistine Revolution: Ethel Mannin, Virginia Woolf and The Battle of the Brows

open access: yesEnglish Literature
The language of the Brows – highbrow, middlebrow and lowbrow – has continued to shape how we think and talk about literature today, with middlebrow remaining the most contested and debated of the three.
Timlin, Carrie
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Working-Class Literature(s): Historical and International Perspectives

open access: yes, 2017
The aim of this collection is to make possible the forging of a more robust, politically useful, and theoretically elaborate understanding of working-class literature(s). These essays map a substantial terrain: the history of working-class literature(s) in Russia/The Soviet Union, The USA, Finland, Sweden, The UK, and Mexico.
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Analyzing the JDP Era through Class Struggles

open access: yesSiyasal: Journal of Political Sciences
Several significant social changes have occurred during the 21-year tenure of the Justice and Development Party (JDP) government in Turkey. However, the scholarship on this period either utterly disregards the working class or depicts it as a passive ...
Mertcan Şafak Sağlam
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

BS Johnson and the Attack of the White-Collar Working Class

open access: yesOpen Library of Humanities
The conventional wisdom around working-class writing often presupposes a realist aesthetic form, a hero employed in manual labour and, in the British context, a setting somewhere in its former industrial heartlands, certainly no further south than the ...
Matti Ron
doaj   +2 more sources

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