Results 181 to 190 of about 16,057,130 (409)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

Is preterm delivery still related to physical working conditions in pregnancy? [PDF]

open access: bronze, 1991
Marie‐Josèphe Saurel‐Cubizolles   +2 more
openalex   +1 more source

Work and the musculoskeletal conditions [PDF]

open access: yesClinical Medicine, 2004
Peter J Maddison, Andrew O. Frank
openaire   +2 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Condiciones laborales en enfermeras de Cartagena, Colombia Nurses working conditions in Cartagena, Colombia Condições de trabalho para enfermeiras de Cartagena, Colômbia

open access: yesAvances en Enfermería, 2010
Objetivo: identificar las condiciones laborales del profesional de enfermería en instituciones de salud en Cartagena, Colombia. Método: se diseñó un estudio descriptivo que incluyó personal de enfermería de instituciones públicas y privadas.
Gómez Bustamante Edna   +1 more
doaj  

Health complaints and working conditions experienced in relation to work and age. [PDF]

open access: bronze, 1996
J.P.J. Broersen   +4 more
openalex   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

open access: yesMolecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach   +8 more
wiley   +1 more source

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