Results 101 to 110 of about 6,375,807 (304)

Analysis of Brayton Cycle Characteristics of CO2-SF6 Mixed Working Fluid

open access: yesYuanzineng kexue jishu, 2023
The supercritical carbon dioxide (S-CO2) Brayton cycle is an efficient energy conversion system. It has the advantages of simple and compact, low noise and high efficiency.
XI Dapeng;LIU Minyun;LIU Xiuting;FEI Junjie;ZANG Jinguang;HUANG Yanping
doaj  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Multi-objective synergistic optimization of closed Brayton cycle superstructure for thermal protection system of high-Mach-number air-breathing vehicles

open access: yesCase Studies in Thermal Engineering
The power generation and cooling Brayton cycle system promises to resolve the thermal protection and electricity demand of high-Mach-number air-breathing vehicle engines. A new design challenge arises from the trade-off between the cooling capability and
Chendi Yang   +6 more
doaj   +1 more source

Comparison of the energetic performance of a binary cycle and a flash evaporation binary cycle, using low-enthalpy geothermal energy

open access: yesInternational Journal of Sustainable Engineering, 2017
In this article, the comparison of the energetic performance of a binary cycle and a modified binary cycle with flash evaporation is presented, both using a low-enthalpy geothermal resource.
Héctor Miguel Aviña Jiménez   +2 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Increasing the efficiency of power plants with heat recovery of automotive equipment by using a working substance with optimal physical properties

open access: yesОмский научный вестник: Серия "Авиационно-ракетное и энергетическое машиностроение"
An urgent issue is to increase the efficiency of the internal combustion engine through the use of a Rankine regenerative cycle, which allows converting heat losses into additional useful work, which can lead to lower fuel consumption and resource ...
V. A. Futin
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

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