Results 151 to 160 of about 4,676,319 (282)

Early olfactory pre-conditioning during sensitive developmental periods is associated with enhanced detection performance in working dogs. [PDF]

Vet Res Commun
Durán-Arroyo G, Cuadrado-Gordillo I, Bormann DA, Fernández MJ, Pichilingue-Chalco EJ, Grandjean D.   +5 more
europepmc   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Preliminary Evaluation of a System with On-Body and Aerial Sensors for Monitoring Working Dogs. [PDF]

Sensors (Basel), 2022
Foster M, Wu T, Roberts DL, Bozkurt A.
europepmc   +1 more source

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra, Nagendra K. Rai, Timothy D. Niepokny, Haley Courtney, Ajai Tripathi, Ranjan Dutta   +5 more
wiley   +1 more source

Integrated effects of dietary supplementation of Spirulina platensis in working dogs: nutritional, biochemical, antioxidant, immunological, gut-related microbial and nutrigenomic insights. [PDF]

BMC Vet Res
Abdelhady HA, Yassin AM, Aboul-Ella H, Fahmy KNE, Farghali HAM, M A T.   +5 more
europepmc   +1 more source

Less is more? Ultra-low carbohydrate diet and working dogs' performance. [PDF]

PLoS One, 2021
Gal A, Cuttance W, Cave N, Lopez-Villalobos N, Herndon A, Giles J, Burchell R.   +6 more
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Dogs' Detection of Symptomatic and Asymptomatic SARS-CoV-2 by Non-Working Dogs: Feasibility and Limits Under Controlled Laboratory Conditions. [PDF]

Animals (Basel)
Cattet J, Retornaz F, Munier F, Collignon C, Gaunet F.   +4 more
europepmc   +1 more source

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Take a Look Towards the Stress Response of Working Dogs: Cortisol and Lactate Trend Mismatches During Training. [PDF]

Animals (Basel)
Cocco R, Sechi S, Sisia G, Pinna Parpaglia ML, Rizzo M, Arrigo F, Giannetto C, Piccione G, Arfuso F.   +8 more
europepmc   +1 more source