Results 71 to 80 of about 4,647 (272)

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

The Welfare Aggregation and Guidance (WAG) Tool: A New Method to Summarize Global Welfare Assessment Data for Equids

Animals, 2020
Animal welfare can be represented by an array of indicators. There is, however, increasing demand for concise welfare assessments that can be easily communicated and compared.
Laura M. Kubasiewicz, João B. Rodrigues, Stuart L. Norris, Tamlin L. Watson, Karen Rickards, Nikki Bell, Andrew Judge, Zoe Raw, Faith A. Burden   +8 more
doaj   +1 more source

The Use of Draught Animals in Rural Labour

Animals, 2021
This study discusses scientific findings on the use of draught animals such as equids (i.e., horses, mules, and donkeys) and bovids (i.e., cattle and water buffaloes) in rural labours. Relevant peer-reviewed literature published between 1980 and 2021 was
Daniel Mota-Rojas, Ada Braghieri, Adolfo Álvarez-Macías, Francesco Serrapica, Efrén Ramírez-Bribiesca, Rosy Cruz-Monterrosa, Felicia Masucci, Patricia Mora-Medina, Fabio Napolitano   +8 more
doaj   +1 more source

Lyophilized Synthetic Platelets: In Vitro Characterization and in Vivo Evaluation in Mouse Thrombocytopenia Model

Advanced Science, EarlyView.
ABSTRACT Platelet transfusions to treat bleeding complications use donor‐derived platelets stored at room‐temperature, that have a shelf‐life of only 5–7 days due to bacterial contamination risks. Cold‐stored and freeze‐dried platelets are being investigated for extending shelf‐life, but these still have the inherent challenge of donor‐dependency.
Ujjal Didar Singh Sekhon, Dante Disharoon, Shrijal S. Desai, Baylee Traylor, Emily Gahagan, Emma Quill, Kristin Aldridge, Norman F. Luc, Sonali Rohiwal, Shruti Raghunathan, Rebecca Ahn, Sana Syed, Alexander Dornback, Bipin Chakravarthy Paruchuri, Andrew Ditto, Susan M. Shea, Philip C. Spinella, Matthew D. Neal, Michael A. Bruckman, Christa L. Pawlowski, Anirban Sen Gupta   +20 more
wiley   +1 more source

Using Qualitative Methods to Explore Farrier-Related Barriers to Successful Farriery Interventions for Equine Welfare in India

Animals, 2019
Farriery is a critical component of healthcare services for working equids. However, in India, an informal workforce, lack of structured training facilities and non-implementation of farriery regulations pose challenges for quality farriery. Brooke India,
Dinesh S Mohite, Chand S Sheikh, Saurabh Singh, Jogen Kalita, Shereene Williams, Polly C Compston   +5 more
doaj   +1 more source

Evaluation of long-term welfare initiatives on working equid welfare and social transmission of knowledge in Mexico.

PLoS ONE, 2021
Working equids play an essential role in supporting livelihoods, providing resilience and income security to people around the world, yet their welfare is often poor.
Emily Haddy, Faith Burden, José Antonio Fernando-Martínez, Dafne Legaria-Ramírez, Zoe Raw, Julia Brown, Juliane Kaminski, Leanne Proops   +7 more
doaj   +1 more source

Why the Donkey Did Not Go South: Disease as a Constraint on the Spread of Equus asinus into Southern Africa [PDF]

, 2017
Donkeys are the only ungulate definitely known to have been domesticated in Africa and were widely employed in the north of the continent and through the Sahara and the Sahel as pack animals, as well as spreading through much of the Old World.
Peter Mitchell
core   +2 more sources

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source