Results 51 to 60 of about 5,382,061 (295)
Fluid-particle dynamics of nasal drug delivery in a realistic human airway lung model
, 2022 Nasal drug delivery provides a rapid onset of therapeutic effects due to the nasal route's large surface area, high blood flow, and ease of accessibility.
Francis, Isabella +3 more
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
LOW TEMPERATURES EFFECT ON THERMAL CONDITIONS OF DZ-98 AUTOGRADER HYDRAULIC UNITS
Вестник СибАДИ, 2020 Introduction. The article discusses the climatic conditions of Yakutia, as well as the cooling process of the hydraulic system of DZ-98 motor grader in order to prevent violation of the thermal regime of hydraulic units under the influence of low ...
T. N. Okhlopkov
doaj +1 more source
Physics, 2011 Researchers show how the judicious choice of fluid filler can suppress the turbulent flow that severely hinders the “top-kill” plugging of a blown-out oil well.
openaire +2 more sources
Exergy Analysis of an Absorption Refrigeration System Using an Iconic Liquid as a Working Fluid in the Chemical Compressor [PDF]
, 2012 The first and second law of thermodynamics are applied to an ionic-liquid (IL) based absorption refrigeration system for high power electronics cooling. The IL is a salt in a liquid state usually with an organic cation and inorganic anion. It provides an
Kim, Yoon Jo +4 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Energies, 2019 This paper reviews the applications of the multi-vane expanders in ORC (organic Rankine cycle) systems. The operating principle and design of the ORC systems are addressed in the introduction.
Piotr Kolasiński
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Energies, 2019 The utilisation of low- and medium-temperature energy allows to reduce the energy shortage and environmental pollution problems because low-grade energy is plentiful in nature and renewable as well.
Andrea Colantoni +4 more
doaj +1 more source