Results 91 to 100 of about 396,320 (310)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A closed cycle cascade Joule Thomson refrigerator for cooling Josephson junction magnetometers [PDF]

A closed cycle cascade Joule Thomson refrigerator designed to cool Josephson Junction magnetometers to liquid helium temperature is being developed. The refrigerator incorporates 4 stages of cooling using the working fluids CF4 and He.
Sarwinski, R., Tward, E.
core   +1 more source

Experimental validation of multiphase flow models and testing of multiphase flow meters: A critical review of flow loops worldwide [PDF]

, 2016
Around the world, research into multiphase flow is performed by scientists with hugely diverse backgrounds: physicists, mathematicians and engineers from mechanical, nuclear, chemical, civil, petroleum, environmental and aerospace disciplines ...
Bello, O. O., Falcone, Gioia, Teodoriu, C.   +2 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Hardware-in-the-loop simulation of magnetorheological dampers for vehicle suspension systems

, 2007
Magnetorheological (MR) fluids provide an elegant means to enhance vibration control in primary vehicle suspensions. Such fluids can rapidly modify their flow characteristics in response to a magnetic field, so they can be used to create semi-active ...
Batterbee, D.C., Sims, N.D.
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Global sensitivity analysis of computer-aided molecular design problem for the development of novel working fluids for power cycles [PDF]

, 2015
In recent years there is a large availability of low-temperature heat sources in different applications such as waste heat in chemical industries and refrigeration plants as well as renewable energy sources suchas biomass combustion, geothermal and solar
Aly, Andreasen, Gani, Helton, Iman, Invernizzi, Linke, Liu, Morris, Sin   +9 more
core   +1 more source

Rapid bacterial counts in metal working fluids

Journal of Industrial Microbiology and Biotechnology, 2002
A rapid (10 s) automated fluorescent method to estimate viable bacteria in metal working fluids (MWF) was compared with dip-slide cultures. The BactiFluor method compared favorably with 107 MWF (r=0.99) and with 30 other metal processing fluids.
J L, Sloyer, T J, Novitsky, S, Nugent
openaire   +2 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Facile fabrication of hydrophobic porous monoliths from charge-driven assembled polymers-stabilized high internal phase emulsion for oil spills reclamation

Desalination and Water Treatment
Oil leakage/spillage and discharge of organic liquids pose severely threat to ecological environment and human health. Herein, hydrophobic porous monolith was fabricated via the polymerization of high internal phase emulsions (HIPEs) stabilized from ...
Jingjuan Lai, Haiyan Zhang, Yunong Yang, Xulin Yang, Peng An, Li Wang, Zhenyu Li, Yuanpeng Wu   +7 more
doaj   +1 more source