Results 121 to 130 of about 3,261,650 (290)

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

An analytical model of lateral condylar plate working length. [PDF]

open access: yesClin Biomech (Bristol), 2023
Roytman GR   +10 more
europepmc   +1 more source

Citation Success: Evidence from Economic History Journal Publications [PDF]

open access: yes
This study examines the determinants of citation success among authors who recently published their work in economic history journals. We find that full professors, authors from non-economic history departments, and authors working in Anglo-Saxon ...
Di Vaio, Gianfranco   +2 more
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

open access: yesFEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz   +9 more
wiley   +1 more source

Evaluation of the Accuracy of Electronic Apex Locators in Modern Endodontics: An Umbrella Review

open access: yesMedicina
Background and Objectives: To achieve success in endodontic treatment, it is essential to properly perform the steps of shaping, cleansing and obturation.
Massimo Pisano   +5 more
doaj   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

open access: yesFEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso   +4 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The Willingness to Pay for Job Amenities: Evidence from Mothers' Return to Work [PDF]

open access: yes
This study is the first to estimate mothers’ marginal willingness to pay (MWP) for job amenities directly. Its identification strategy relies on German maternity leave length.
Christina Felfe
core   +3 more sources

Evaluation of the Accuracy of Different Apex Locaters with 45° Apical Root Resorption

open access: yesDentistry 3000
Aim: This study was aimed to calculate the working length (WL) of permanent teeth with simulated 45° resorption of the apical part of the root using four electric apex locaters (EALs): NSK, Woodpecker III, Woodpecker V, and Eighteeth.
Ahmed I Al-Jobory   +2 more
doaj   +1 more source

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