Results 81 to 90 of about 3,261,650 (290)

بررسی بالینی دقت دستگاه آپکس‌یاب الکترونیکی Raypex5 در اندازه‏گیری طول کانال‏ ریشه دندان‏های شیری [PDF]

Journal of Mashhad Dental School, 2011
مقدمه: استفاده از رادیوگرافی جهت تعیین طول کارکرد در کودکان به دلیل مضرات اشعه، تداخل تصویر جوانه دندان دائمی و ریشه دندان شیری، محدودیت باز شدن دهان، عدم همکاری کودک و مشکلات تفسیر رادیوگرافیک در دندان‏های شیری مشکلاست.
الهام خوشبین, طاهره معصوم, سید محسن جلال زاده   +2 more
doaj  

Graphene microwave transistors on sapphire substrates

, 2011
We have developed metal-oxide graphene field-effect transistors (MOGFETs) on sapphire substrates working at microwave frequencies. For monolayers, we obtain a transit frequency up to ~ 80 GHz for a gate length of 200 nm, and a power gain maximum ...
A. C. Betz, B. Plaçais, C. Benz, E. Pallecchi, H. v. Löhneysen, Lee J., Lin Y.-M., Lin Y.-M., Meric I., Pozar D. M., R. Danneau   +10 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Comparison of digital radiography and apex locator with the conventional method in root length determination of primary teeth

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Aim: The purpose of this study was to compare the Working length in primary teeth endodontics using intra oral digital radiovisiography and apex locator with conventional method for accuracy.
I E Neena, A Ananthraj, P Praveen, V Karthik, P Rani   +4 more
doaj   +1 more source

Designing the Optimal Length of Working Time [PDF]

How many hours per week should workers in the United States and Germany spend at their paying jobs? The present paper addresses this question by constructing policymakers’ reaction functions capable of modelling the optimal length of working time as a ...
Antonio Garofalo, Carlo Altavilla, Concetto Paolo Vinci   +2 more
core  

Fully Online Grammar Compression in Constant Space

, 2014
We present novel variants of fully online LCA (FOLCA), a fully online grammar compression that builds a straight line program (SLP) and directly encodes it into a succinct representation in an online manner. FOLCA enables a direct encoding of an SLP into
Maruyama, Shirou, Tabei, Yasuo
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source