Results 71 to 80 of about 114,521 (253)

Comparison of working length determination using apex locator and manual method - ex vivo study

Dentistry and Medical Research, 2016
Background: Electronic apex locators can be a useful adjunct with a high level of accuracy for determining the real root canal length in clinical practice.
Jhadye Alves Carneiro, Fredson Marcio Acris de Carvalho, Andre Augusto Franco Marques, Emilio Carlos Sponchiado Junior, Lucas da Fonseca Roberti Garcia, Leonardo Cantanhede Oliveira Goncalves   +5 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

A novel noninvasive radiographic working length determination method – A randomized controlled clinical trial

Endodontology
Aim: This randomized controlled clinical trial compared a novel, noninvasive radiographic method with a fourth-generation electronic apex locator (EAL) for working length determination.
Joseph Minu, Anand V. Susila, Aruna Kumari Veronica   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Evaluating the Accuracy of Deep Learning Models and Dental Postgraduate Students in Measuring Working Length on Intraoral Periapical X-rays: An In vitro Study

Contemporary Clinical Dentistry
Background: The integration of artificial intelligence in dentistry has seen remarkable advancements, especially in diagnostic imaging. This study evaluates and compares the accuracy of deep learning models with that of dental postgraduate students in ...
R. S. Basavanna, Ishaan Adhaulia, N. M. Dhanyakumar, Jyoti Joshi   +3 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Tactile Method for Orthograde Exploration of the Apical Foramen in Non-vital Permanent Teeth with Open Apices: Case Series

European Endodontic Journal
This research assessed the interobserver agreement and precision of the tactile method (TM) during orthograde exploration of the apical terminal portion of permanent teeth with necrotic pulps and open apices.
Marlen Arroyo Tovar, Hugo Plascencia, Mariana Díaz, Andres Olvera Bravo, Mario Uribe, Gerardo Gascon, Rodrigo Solis   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source