Results 101 to 110 of about 2,005,023 (278)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Long-term memory effects on working memory updating development.

open access: yesPLoS ONE, 2019
Long-term memory (LTM) associations appear as important to cognition as single memory contents. Previous studies on updating development have focused on cognitive processes and components, whereas our investigation examines how contents, associated with ...
Caterina Artuso, Paola Palladino
doaj   +1 more source

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick   +14 more
wiley   +1 more source

Effects of problem size, operation, and working-memory span on simple-arithmetic strategies: differences between children and adults? [PDF]

open access: yes, 2008
Adult’s simple-arithmetic strategy use depends on problem-related characteristics, such as problem size and operation, and on individual-difference variables, such as working-memory span.
Imbo, Ineke, Vandierendonck, André
core   +1 more source

Understanding jumping to conclusions in patients with persecutory delusions: working memory and intolerance of uncertainty

open access: yes, 2014
Background. Persecutory delusions are a key psychotic experience. A reasoning style known as ‘jumping to conclusions’ (JTC) – limited information gathering before reaching certainty in decision making – has been identified as a contributory factor in the
Cordwell, J.   +8 more
core   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin   +11 more
wiley   +1 more source

Working Memory From the Psychological and Neurosciences Perspectives: A Review

open access: yesFrontiers in Psychology, 2018
Since the concept of working memory was introduced over 50 years ago, different schools of thought have offered different definitions for working memory based on the various cognitive domains that it encompasses.
Wen Jia Chai   +4 more
doaj   +1 more source

Relationships between working memory, expressive vocabulary and arithmetical reasoning in children with and without intellectual disabilities. [PDF]

open access: yes, 2003
This experiment examined the relationships between working memory and two measures of achievement, namely expressive vocabulary and arithmetical reasoning, in children with and without intellectual disabilities (ID).
Henry, Dr Lucy, MacLean, Ms Morag
core  

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron   +5 more
wiley   +1 more source

Working Memory Training for Schoolchildren Improves Working Memory, with No Transfer Effects on Intelligence

open access: yesJournal of Intelligence, 2017
Working memory contributes to many higher-order cognitive processes and predicts general cognitive skills. It is therefore important to know if its functions are trainable.
Dorota Żelechowska   +2 more
doaj   +1 more source

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