Results 71 to 80 of about 339,608 (268)

Working Memory 2.0 [PDF]

open access: yesNeuron, 2018
Working memory is the fundamental function by which we break free from reflexive input-output reactions to gain control over our own thoughts. It has two types of mechanisms: online maintenance of information and its volitional or executive control. Classic models proposed persistent spiking for maintenance but have not explicitly addressed executive ...
Earl K, Miller   +2 more
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Simple and Complex Working Memory Tasks Allow Similar Benefits of Information Compression

open access: yesJournal of Cognition, 2018
Complex working memory span tasks were designed to engage multiple aspects of working memory and impose interleaved processing demands that limit the use of mnemonic strategies, such as chunking.
Fabien Mathy   +2 more
doaj   +1 more source

Math Anxiety and Working Memory Updating: Difficulties in Retrieving Numerical Information From Working Memory

open access: yesFrontiers in Psychology, 2020
This study aimed to determine whether math anxiety was related to working memory (WM) updating performance and, specifically, to the retrieval and substitution components of updating.
Santiago Pelegrina   +3 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Auditory Working Memory [PDF]

open access: yes, 2018
This chapter reviews behavioral and neuroimaging\ud fndings on:\ud 1. The comparison between verbal and tonal\ud working memory (WM)\ud 2. The infuence of musical training\ud 3. The role of sound mimicry and auditory memory\ud 4. The infuence of long-term memory (LTM) on\ud auditory WM performance, i. e., the efect of\ud strategy use on auditory WM.\ud
Schulze, K., Koelsch, S., Williamson, V.
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Uma introdução ao estudo cognitivo da memória a curto prazo: da teoria dos múltiplos armazenadores a memória de trabalho

open access: yesEstudos de Psicologia (Campinas)
Este artigo apresenta uma revisão teórica dos principais estudos publicados a respeito do sistema de memória a curto prazo. A primeira parte deste artigo trata de uma revisão histórica do estudo da memória a curto prazo.
Márcia da Mota
doaj   +1 more source

Habitual prospective memory in schizophrenia

open access: yesBMC Psychiatry, 2003
Background Prospective memory (PM), the act of remembering that something has to be done in the future without any explicit prompting to recall, provides a useful framework with which to examine problems in internal-source monitoring.
Maylor Elizabeth A   +2 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

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