Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Managing Sustainable Working Hours within Participatory Working Time Scheduling for Nurses and Assistant Nurses: A Qualitative Interview Study with Managers and Staffing Assistants. [PDF]
Epstein M +3 more
europepmc +1 more source
A Comparative Analysis of the Working Time Estimation Methods
The problem of working time standardization attracts the attention of the managers of Latvian sewing enterprises since it is the main condition to reduce working time consumption.
Rumjanceva, Tatjana +2 more
core
Working time policy in France [PDF]
Working time has always been considered in France to be an area of responsibility for the State. TheActs on the 35-hour working week come therefore from a long tradition of State intervention toregulate employment and working conditions.
Pierre Boisard
core
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Working time reduction, mental health, and early retirement among part-time teachers at German upper secondary schools - a cross-sectional study. [PDF]
Seibt R, Kreuzfeld S.
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Single-phase Fe<sub>0.5</sub>Co<sub>0.5</sub>S<sub>2</sub> cathode material for long working time thermal batteries. [PDF]
Yang H +5 more
europepmc +1 more source
Analysis on personnel costs and working time for implementing a more person-centred care approach: a case study with embedded units in a Swedish region. [PDF]
Gyllensten H +3 more
europepmc +1 more source

