Results 121 to 130 of about 3,268,504 (304)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Sickness Absence, Works Councils, and Personnel Problems. Evidence from German Individual and Linked Employer-Employee Data [PDF]

open access: yes, 2013
Using both household and linked-employer-employee data we study the effects of works councils on individual sickness absence rates and a subjective measure of personnel problems due to absenteeism in Germany. We find that the existence of a works council
Arnold, Daniel   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Testing the nonlinearity of the BVIcJHKs period-luminosity relations for the Large Magellanic Cloud Cepheids

open access: yes, 2007
A number of recent works have suggested that the period-luminosity (PL) relation for the Large Magellanic Cloud (LMC) Cepheids exhibits a controversial nonlinear feature with a break period at 10 days.
Kanbur, S., Nanthakumar, A., Ngeow, C.
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

PERENCANAAN ULANG STRUKTUR GEDUNG FAKULTAS ILMU KOMPUTER UNIVERSITAS BRAWIJAYA DENGAN BAJA KOMPOSIT MENGGUNAKAN SISTEM PENAHAN GEMPA BRACING (Studi Perencanaan : Manajemen Konstruksi) [PDF]

open access: yes
When constructing a building, careful budget planning (RAB) and implementation schedule planning are required, both on a small and large scale. In the Lecture Building for the Faculty of Computer Science, Brawijaya University, located in Malang City, it ...
Rizaldi, Ahmad
core  

Freedom of Information Act Performance, 2012: Agencies Are Processing More Requests but Redacting More Often [PDF]

open access: yes, 2013
A building block of American democracy is the idea that citizens have a right to information about how their government works and what it does in their name.
Gavin Baker, Sean Moulton
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Boston University Wind Ensemble, April 25, 1996 [PDF]

open access: yes, 1996
This is the concert program of the Boston University Wind Ensemble performance on Thursday, April 25, 1996 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts.
School of Music, Boston University
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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