Results 31 to 40 of about 333,323 (263)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Optical Low Resolution Spectroscopic Observations of T Pyx during the Early Phase of 2011 Outburst

open access: yesActa Polytechnica CTU Proceedings, 2015
We report on the results of our low resolution spectroscopic observations during the 2011 outburst of the recurrent nova T Pyx. Our observations were performed from 0.19 days to 34 days after the eruption discovered by M. Linnolt.
A. Arai   +4 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Evolution of the Stability Work from Classic Retaining Walls to Mechanically Stabilized Earth Walls [PDF]

open access: yesBulletin of the Polytechnic Institute of Jassy: Constructions, Architechture Section, 2008
For the consolidation of soil mass and the construction of the stability works for roads infrastructure it was studied the evolution of these kinds of works from classical retaining walls - common concrete retaining walls, to the utilization in our days ...
Anghel Stanciu, Oana Colţ
doaj  

A Case of Janumet Poisoning [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2017
Janumet, an anti-diabetic drug is being increasingly used. Each tablet contains 50 mg of sitagliptin + 500/1000 mg of metformin. Metformin works by decreasing glucose production in the liver and decreasing absorption of glucose by the intestines ...
Arun Bahulikar   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

E.R. Dodds’ Lecture Notes on Hesiod’s Works and Days

open access: yesHistory of Classical Scholarship, 2019
This article offers the text of a lecture on Hesiod’s Works and Days written by Eric Robertson Dodds, along with transcriptions of the extensive marginalia he wrote in his copy of Frederick A. Paley’s edition of the poems.
Ben Cartlidge
doaj  

ABOUT HOLINESS AND PIETY IN MODERN ARABIC LITERATURE

open access: yesКонцепт: философия, религия, культура, 2019
These chapters are taken from monographies of N. Uspenskaya “East – West – Russia: the protheses of culture interaction”. In these chapters the author touches the themes of holiness and piety, faith and national conciseness, spirituality and intercourse ...
N. A. Uspenskaya
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

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