Results 151 to 160 of about 134,291 (283)

Intercellular Horizontal Transfer of TXNDC5 mRNA via Extracellular Vesicles Contributes to Tumor‐Associated Macrophage‐Mediated Prostate Cancer Metastasis

Advanced Science, EarlyView.
This study investigates the role of M2 macrophage‐derived extracellular vesicles (M2 EVs) in prostate cancer (PCa) metastasis. Mechanistically, M2 EVs horizontally transfer TXNDC5 mRNA to PCa cells, where the molecule induces the mesenchymal‐like state (MLS), enhancing PCa migration and invasion.
Cong Hu, Tianyang Wu, Jiayi Wang, Xinxing Du, Xinrui Wu, Yanhao Dong, Zehong Peng, Penghui Liao, Zirui Guo, Zheyu Liu, Kenneth J Pienta, Yinjie Zhu, Jiahua Pan, Liang Dong, Wei Xue   +14 more
wiley   +1 more source

How to lead world society towards sustainable development? [PDF]

In political terms it all started with the World Commission on Environment and Development which in its 1987 report Our Common Future stated that ...humanity has the ability to make development sustainable - to ensure that it meets the needs of the ...
Simonis, Udo E.
core  

WORLD ECOLOGIC REVOLUTION

GISAP:Sociological, Political and Military Sciences, 2014
openaire   +1 more source

Genomics Insights Into High‐Latitude Adaptation of Tibetan Macaques

Advanced Science, EarlyView.
Tibetan macaques exhibit unique adaptations to cold, high‐latitude environments, including shortened tails and enhanced fat storage. Genomic analyses reveal a species‐specific TBX6 mutation linked to tail reduction and selection on lipid metabolism genes.
Rusong Zhang, Ying Hu, Yang Teng, Jiwei Qi, Yangzhen Ciren, Lin Zhang, Qiao Du, Wencai Xu, Liang Zhou, Zhenxin Fan, Jinchuan Xing, Ming Li, Jing Li   +12 more
wiley   +1 more source

Different Methodologies Result in Opposite Patterns of Diversification Rates in Flowering Plants Across Latitudes. [PDF]

Ecol Evol
Qian H, Kessler M.
europepmc   +1 more source

Precision Editing of NLRS Improves Effector Recognition for Enhanced Disease Resistance

Advanced Science, EarlyView.
Precision engineering of plant NLR immune receptors enables rational design of enhanced pathogen resistance through mismatched pairing, domain swapping, and targeted mutagenesis. These approaches achieve multi‐fold expansion in recognition breadth while minimizing autoimmunity risks and fitness penalties.
Vinit Kumar, Vishwa I. P. W. A. Kumara, Pradeepa C. G. Bandaranayake, Dong Yawen, Yang‐Yang Gao, Junfeng Liu, Ge‐Fei Hao, Xiu‐Fang Xin   +7 more
wiley   +1 more source

Functional motifs in food webs and networks. [PDF]

Proc Natl Acad Sci U S A
Habermann M, Fahimipour AK, Yeakel JD, Gross T.   +3 more
europepmc   +1 more source

THE “STOCK AND FLOW” APPROACH TO THE GOVERNANCE OF SELF-SUSTAINABLE RURAL SYSTEMS [PDF]

The aim of this study is to present the “stock and flow” model - based on the Georgescu-Roegen bio economic paradigm and on the ecological economics principles - in a regional key and to discuss the implications of such an approach on the local system ...
Bonaiuti, M., Franco, Silvio, Pancino, Barbara   +2 more
core   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

Advances in Molecular Microbiology-From Recent Advances to the Future. [PDF]

Curr Issues Mol Biol
Seal BS.
europepmc   +1 more source