Results 171 to 180 of about 134,291 (283)

Beyond the patch: leveraging functional habitat delineation in fragmentation-biodiversity research. [PDF]

Landsc Ecol
Dennis M, Huck J, Holt C, McHenry E, Andersson E, Sharma S, Haase D.   +6 more
europepmc   +1 more source

Justice Scenographics: Preparing for civilization change in a time of ‘Anywheres’ and ‘Somewheres’ [PDF]

, 2020
Hann, Rachel
core  

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Modelling the impact of modes of governance on territorial dynamics: the case of the oil palm in lndonesia [PDF]

, 2017
Bessou, Cécile, Bosc, Pierre-Marie, Wohlfahrt, Julie   +2 more
core  

Identification and Characterization of an In Silico Designed Membrane‐Active Peptide with Antiviral Properties

Advanced Science, EarlyView.
An evolutionary molecular dynamics platform is used to design P1.6, a membrane‐active peptide that senses lipid packing defects in viral envelopes. P1.6 adopts a stabilized α‐helical structure upon membrane contact, disrupts virus‐like liposomes, and damages HIV‐1 particles.
Pascal von Maltitz, Niek van Hilten, Tatjana Weil, Thunchanok Thummaraj, Jeroen Methorst, Dennis Aschmann, Alexander Kros, Clarissa Read, Jasmina Gačanin, Herre Jelger Risselada, Jan Münch   +10 more
wiley   +1 more source

Plant community data along elevational gradients in China's 17 mountains. [PDF]

Sci Data
Wang X, Chen Y, Chen Y, Ding Y, Fang S, Hao Z, He Z, Hu G, Jia S, Li B, Lin F, Liu J, Liu L, Luo Y, Luo Y, Shen Y, Song H, Song K, Tian Z, Xing D, Yang Q, Yang X, Yang Y, Yuan Z, Yuan Z, Zhang Q, Zhang Z, Zhang Z, Zhang J.   +28 more
europepmc   +1 more source

Innovation financing in the agricuktural sector [PDF]

, 2020
Bazhanova, Nataliia, Horbachova, Oksana, Nehoda, Yuliia, Rybina, Larysa, Shaiyhina, Iryna, Tytarchuk, Iryna   +5 more
core  

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

Unlocking potential: Development finance reforms needed to support localized health product manufacturing. [PDF]

PLOS Glob Public Health
Lynch S, Adetifa I, Dong J, Matiru R, Parshall C.   +4 more
europepmc   +1 more source

Quantitative Proteomics and CRISPR/Cas9 Editing Reveal UPR‐Mediated Control of Immunoglobulin Homeostasis in Hybridomas

Advanced Science, EarlyView.
BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou, Xinying Lu, Ying Liu, Peiyu Yang, Shuo Sun, Yihua Liu, Yinyuan Mo, Guonian Zhu, Jae Seong Lee, Yirong Guo   +9 more
wiley   +1 more source